The mature heart valves are made up of highly organized extracellular matrix ECM and valve interstitial cells VIC surrounded by an endothelial cell layer. The ECM of the valves is stratified into elastin-, proteoglycan- and collagen-rich layers that confer distinct biomechanical properties to the leaflets and supporting structures. Signaling pathways have critical functions in primary… Read More »
This is part of our Coronavirus Update series in which Harvard specialists in epidemiology, infectious disease, economics, politics, and other disciplines offer insights into what the latest developments in the COVID-19 outbreak may bring. Though fever, cough, and shortness of breath are the symptoms most commonly associated with COVID-19 infection, a recent study in which… Read More »
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Coronavirus has killed more than 40,000 people in the UK, with the number continuing to rise. But, scientists have made a breakthrough in the search for a COVID-19 vaccine. The NHS has been backed to immediately use the dexamethasone steroid as a treatment for coronavirus. The drug has been revealed to lower the risk of… Read More »