Can taking estrogen cause weight loss

By | June 28, 2020

can taking estrogen cause weight loss

December 17, Overall, the majority of trials reviewed showed no and satiety states to ensure. Acknowledgments We appreciate the technical assistance that Bucky Harris and effect of ET on leptin.

Leptin, a hormone secreted by adipocytes, plays a crucial role in regulating energy balance. Estrogen, like leptin, reduces food intake and adiposity while increasing energy expenditure in animals and humans of both sexes through its actions in the central nervous system. We reviewed the literature for studies of the effect of exogenously administered estrogen on serum leptin concentrations and adiposity in women. Studies were further evaluated to determine if leptin and adiposity were monitored both at baseline and throughout a treatment period of at least two months. Twenty articles met inclusion criteria. We found no consistent effect of exogenous estrogen on serum leptin concentrations, adiposity, or weight gain. Despite suggestive data from animal studies, current literature does not provide compelling evidence that estrogen therapy attenuates weight gain, alters circulating leptin levels, or improves leptin action in postmenopausal women. In humans, signaling molecules and feedback systems regulate food consumption and satiety states to ensure that energy intake matches energy expenditure over time, a process called energy homeostasis.

Weight gain is a common concern among aging women. Ekta Kapoor, M. Cardiovascular disease is the leading cause of mortality in postmenopausal women, and the importance of risk factor modification cannot be overemphasized. However, when women ask specifically about the impact of hormone therapy on weight gain during menopause, the answer is much more complicated because of the complex interactions of their symptoms with age-related changes. There has been a debate about the relative contribution of aging versus menopause to weight gain in midlife women. Stephanie S.

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