Tag Archives: Oral

Oral Allopregnanolone Analogue for Postpartum Depression Treatment

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of postpartum depression (PPD).  SAGE-547, now called brexanolone, is a neurosteroid, an analogue of allopregnanolone and an allosteric modulator of GABAA receptors.  Since that time, Sage Therapeutics has conducted three randomized controlled trials, enrolling a total of 247 women diagnosed… Read More »

Oral Appliance Therapy – All You Ought to Know

Obstructive sleep apnea is a sleep disorder where a person stops breathing periodically due to collapsing soft tissue in the airway throughout the night. These stops in breathing usually last for around ten seconds and are often followed by snorts, gasps, or choking sounds as a person’s body fights to resume breathing again. The obstructive… Read More »