Why does diabetes cause osteomyelitis

By | June 11, 2020

why does diabetes cause osteomyelitis

Metrics details. Osteomyelitis is an infection in a bone. Acute osteomyelitis is observed mainly in the long leg bones of children and is usually treated with antibiotics. On the other hand, in adults, subacute or chronic osteomyelitis is more common. Antibiotics therapy is not necessarily effective for chronic osteomyelitis, and sometimes a surgical operation is performed for its remission. Furthermore, in classification of osteomyelitis by cause, type 2 diabetes mellitus is one of most common conditions associated with osteomyelitis.

SI and TA researched data and wrote the manuscript. Predictors of outcomes in diabetic foot osteomyelitis treated initially with conservative nonsurgical medical management: a retrospective study. Surgical Debridement In addition to antimicrobial therapy, adequate surgical debridement is necessary to cure chronic osteomyelitis, because systemic antibiotics do not penetrate devascularized bone fragments; immobilization is also important in both acute and chronic osteomyelitis. Tigecycline Tygacil. The ultimate goal of treatment is to achieve limb salvage wherever possible in the diabetic patient. Therefore, we started 3. Conclusions Here we report a case of chronic osteomyelitis under poorly controlled diabetic conditions. The gold standard for the diagnosis of osteomyelitis is the bone biopsy which provides histological and microbiological findings[ 21, 22 ]. Antibiotics versus conservative surgery for treating diabetic foot osteomyelitis: a randomized comparative trial.

Patient information: See related handout on diabetic foot infections, written by the authors of this article. See the CME Quiz. Diabetic foot infection, defined as soft tissue or bone infection below the malleoli, is the most common complication of diabetes mellitus leading to hospitalization and the most frequent cause of nontraumatic lower extremity amputation. Diabetic foot infections are diagnosed clinically based on the presence of at least two classic findings of inflammation or purulence. Infections are classified as mild, moderate, or severe. Most diabetic foot infections are polymicrobial. The most common pathogens are aerobic gram-positive cocci, mainly Staphylococcus species. Osteomyelitis is a serious complication of diabetic foot infection that increases the likelihood of surgical intervention. Treatment is based on the extent and severity of the infection and comorbid conditions.

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