Tag Archives: depression

Maternal Depression, But Not Exposure to SSRIs, Associated with Worse Executive Functioning in Children  

While we have considerable data on the use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy, most of this research focuses on the risk of congenital malformations in exposed children.  We have far less information regarding the long-term effects of SSRI antidepressants on neurodevelopmental outcomes in exposed children. A recent study looks at executive functioning… Read More »

Oral Allopregnanolone Analogue for Postpartum Depression Treatment

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of postpartum depression (PPD).  SAGE-547, now called brexanolone, is a neurosteroid, an analogue of allopregnanolone and an allosteric modulator of GABAA receptors.  Since that time, Sage Therapeutics has conducted three randomized controlled trials, enrolling a total of 247 women diagnosed… Read More »

Black Caregivers Less Likely to Suffer From Depression

Caring for a loved one with cancer can be emotionally taxing. But Black caregivers are less likely to experience distress or depression than white caregivers, according to new findings presented at the 11th American Association for Cancer Research (AACR) Cancer Conference, reports AACR. Researchers enrolled 44 African-American and 46 white informal caregivers—family or friends as… Read More »