Tag Archives: depression

What to know about depression with psychosis

Depression with psychotic features is when someone experiences both depression and psychosis. Psychosis refers to a disconnection from reality and may include symptoms such as hallucinations or delusions. Major depression with psychotic features is also sometimes referred to as psychotic depression. It is a grave illness characterized by a combination of unipolar major depressive symptoms… Read More »

Brexanolone for Postpartum Depression: More Data, But Still Some Questions

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of severe postpartum depression (PPD).  SAGE-547, now called brexanolone, is an allosteric modulator of GABA-A receptors.  We saw the preliminary results of the Sage Therapeutics Phase 3 Hummingbird Program earlier this year.  Now we have the final set of results… Read More »

Urologic conditions lead to depression, sleep issues in men

Men who have erectile dysfunction, prostate problems, or other urologic conditions are often at higher risk for depression and sleep disorders. Physicians need to screen for this and refer them for specialist care. Men with urologic conditions such as erectile dysfunction are more likely to have depression and sleep disorders. This was the main conclusion… Read More »