Tramadol is a prescription medication commonly used to manage moderate to severe pain. It is classified as an opioid analgesic, but its chemical structure and effects are somewhat different from other opioids. While tramadol can be effective for pain relief, it’s important to understand its safety profile, potential side effects, and risks associated with its… Read More »
It is a central analgesic with a low affinity for opioid receptors. Its selectivity for mu receptors has recently been demonstrated, and the M1 metabolite of tramadol, produced by liver O-demethylation, shows a higher affinity for opioid receptors than the parent drug. The rate of production of this M1 derivative O-demethyl tramadol, is influenced by… Read More »
by neil-farnworth Physical pain is one of the worst things in the world to face. No matter where you have the pain, it makes you weak not just physically but mentally and psychologically too. Any kind of severe pain that is intense enough to be felt by your body makes you vulnerable to irritation and… Read More »